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Research Interests

Our research aims to understand the fundamental principles governing human oocyte and early embryo biology. We investigate the cellular and molecular mechanisms that determine developmental competence, genome stability, and reproductive success.

Using human material alongside complementary mouse and bovine models, and integrating advanced imaging technologies with molecular profiling approaches, we examine how cellular architecture, chromosome dynamics, and regulatory networks shape early development.

Bridging basic cell biology with clinically relevant questions, our work connects mechanistic discovery with translational challenges in reproductive medicine, including infertility and reproductive ageing.

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PharmDr. Zuzana Holubcová, Ph.D.

Principal Investigator

Assistant Professor

Senior Lecturer

Head of Gametogenesis and early Embryo Development Research Group

 

e-mail: zholub@med.muni.cz

 

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ORCiD

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MUDr. Volodymyr Porokh, Ph.D.

Junior Principal Investigator

Genetic Stability and Embryo Patterning Group

 

e-mail: volodymyr.porokh@med.muni.cz

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Address:

Masaryk University Campus | building E24 - Biology Park | 

Studentská 812/6 | 625 00 Brno | Czech Republic

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