Funding
ONGOING
- 01/2025-12/2027
Subcellular Biogenesis and Trafficking of Exosomes in the Context of Alzheimer´s Disease with a Specific Focus on SORL1
Principal Investigator: prof. Hof Martin Dr. rer. nat., DSc.
CO-PI: MSc. Petr Fojtík, Ph.D.
Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA25-16481S
- 01/2025
Advanced Induced Pluripotent Stem Cell Lines for Alzheimer’s Disease Modelling
Principal Investigator: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Masaryk University, Brno, Czech Republic
Grant Number: MUNI/LF-ACC/1430/2024
- 05/2024-12/2027
Unraveling Molecular Mechanisms of Glioblastoma Treatment Resistance and Recurrence: Insights from a 3D GLICO Model
Principal Investigator: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Ministry of Health
Grant Number: NW24-08-00157
- 05/2024-12/2027
Brain organoids for target detection for precision treatment of schizophrenia
Principal Investigator: prof. MUDr. Tomáš Kašpárek, Ph.D.
CO-PI: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Ministry of Health
Grant Number: NW24-04-00158
- 05/2024-12/2027
The function of FGFR2 cilia localization in glioblastoma pathogenesis
Principal Investigator: M.Sc. Michaela Bosáková, Ph.D.
CO-PI: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Ministry of Health
Grant Number: NW24-08-00364
- 01/2024-12/2026
Prioritization of pathways linking aging and Alzheimer’s disease to cognitive decline and dementia
Partner: MSc. Dáša Bohačiaková, Ph.D.
Institutions: Amsterdam UMC / Aarhus University / Max-Planck Institute of Biophysics / The University of Bonn / University Hospital of Köln / University of Luxembourg / Masaryk University...
Funding agency: Ministry of Education Youth and Sports, Czech Republic - Joint Programme
Grant Number: JPND2023-087
- 01/2024-12/2026
Constructing the Developmental Atlas of Alzheimer’s Disease using Cerebral Organoids and Single-Cell Transcriptomics
Principal Investigator: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA24-12028S
- 01/2024-12/2026
Development of brain organoid models to study the role of cellular senescence in the pathogenesis of glioblastoma
Principal Investigator: MUDr. Zdeněk Hodný, CSc.
CO-PI: MSc. Dáša Bohačiaková, Ph.D.
Institution: Czech Academy of Sciences/University hospital Hradec Králové/Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA24-11357S
- 01/2024-12/2026
Humanized platform based on organoids for modeling mRNA-based therapeutic intervention in ischemic brain damage
Principal Investigator: Ing. Lukáš Valihrach, Ph.D.
CO-PI: M.Sc. Tereza Váňová, Ph.D., MSc. Dáša Bohačiaková, Ph.D.
Institution: Czech Academy of Sciences/Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA24-11364S
- 01/2023–12/2026
ADDIT-CE: Alzheimer's Disease Diagnostics Innovation and Translation to Clinical Practice in Central Europe
Funding agency: European Union/Horizon Europe
Grant Number: 101087124
- 07/2022-12/2025
National institute for Neurological Research
- 05/2022-12/2025
Tracking SORLA function in patients with early onset Alzheimer’s disease
Principal Investigator: Jan Raška, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Ministry of Health, Czech Republic
Grant Number: NU22J-08-00075
- 05/2021-12/2024
Pathogen-induced senescence as the initiation trigger for the onset of Alzheimer’s disease
Principal Investigator: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Ministry of Health, Czech Republic
Grant Number: NU21-08-00373
CLOSED
01/2022-12/2023
Career Restart - Next generation sequencing in neural development and disease
Principal Investigator: Katerina Amruz Cerna, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of Masaryk University (GAMU)
Grant Number: MUNI/R/1321/2021
01/2021-12/2023
Uncovering molecular mechanisms of Alzheimer’s disease initiation using brain organoids
Principal Investigator: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA21-21510S
07/2020-12/2023
Identifying and treating SORL1-associated Alzheimer’s disease
Coordinator (Consortium): Henne Holstege
Partner: Dasa Bohaciakova, Ph.D.
Institutions: Amsterdam UMC, The Netherlands / Aarhus University, Denmark / Max-Planck Institute of Biophysics, Germany / Masaryk University, Brno, Czech Republic
Funding agency: The Netherlands Organization for Healthy, Research and Development / Innovation Fund Denmark / Ministry of Education Youth and Sports, Czech Republic / Federal Ministry of Education and Research, Germany
Grant Number: 8F20009
01/2021-12/2022
Career Restart - Stem Cell-Based Models of Neurodegeneration
Principal Investigator: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of Masaryk University (GAMU)
Grant Number: MUNI/R/1697/2020
01/2020-12/2022
New approaches to overcome therapeutic resistance of glioblastoma multiforme: Focus on cellular senescence and cerebral organoid model
Principal Investigator: Zdeněk Hodný, M.D., Ph.D.
CO-PI: Dasa Bohaciakova, Ph.D.
Institution: Institute of Molecular Genetics / University Hospital Hradec Kralove / Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA20-15728S
05/2019 – 12/2022
Clinically relevant biochemical, immunological and cellular biomarkers of Alzheimer's disease and aging
Principal Investigator: Pharm.Dr. Zdeněk Spáčil, Ph.D.
CO-PI: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Ministry of Health Research Programme 2015 - 2022
Grant Number: NV19-08-00472
10/2020-09/2021
Neuronální excitabilita jako klíč k patofyziologii řady neuropsychiatrických onemocnění: snímání aktivity in vitro modelů lidské nervové tkáně technikou multielektrodových polí
Principal Investigator: doc. MUDr. Markéta Bébarová, Ph.D.
CO-PI: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic
Funding agency: Grant Agency of Masaryk University (GAMU)
Grant Number: MUNI/11/SUP/07/2020
03/2018 – 2020
Title: Transformative stem cell-based model of Alzheimer’s disease and advanced analytics to study the role of membrane lipids in the pathogenesis
Principal Investigator: Zdenek Spacil, PhD
Co-PI: Dasa Bohaciakova, PhD
Funding agency: Grant Agency of Masaryk University (GAMU)
2018 – 2020
Functional studies of miRNAs and protein-coding genes involved in stem cell specification during neural development.
Principal Investigator: Dasa Bohaciakova, PhD
Funding agency: Grant Agency of the Czech Republic (GACR)
2018/01 – 2019/06
Klinicky-využitelné neurální kmenové buňky a studium řízení jejich buněčného dělení.
Principal Investigator: Dasa Bohaciakova, PhD
Funding agency: Fond Neuron na podporu vedy - Neuron Impuls
2017
In vitro modelování patologie Alzheimerovy choroby pomocí cerebrálních organoidů
Institutional support by Faculty of Medicne MU for junior researchers (2017, PI)
2015 – 2017
The role of microRNA in cell cycle regulation and differentiation of human embryonic stem cell-derived neural stem cells.
Principal Investigator: Dasa Dolezalova, PhD
Funding agency: Grant Agency of the Czech Republic (GACR)
2016
The role of microRNAs in the biology of human embryonic stem cells
Institutional support by Faculty of Medicine MU for junior researchers (2016, PI)
2009 - 2010
The role of microRNAs and protein-coding genes in human embryonic stem cell response to DNA damage.
Principal Investigator: M.Sc. Dasa Dolezalova
Funding agency: Grant Agency of Masaryk University (GAMU)
2007 - 2009
Analysis of Effects of Inhibition of Cyclin-Dependent Kinases on Differentiation of Human Embryonic Stem Cells.
Principal Investigator: Bc. Dasa Dolezalova
Funding agency: Grant Agency of Masaryk University (GAMU)