Funding

ONGOING

  • 05/2024-12/2027

Unraveling Molecular Mechanisms of Glioblastoma Treatment Resistance and Recurrence: Insights from a 3D GLICO Model

Principal Investigator: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Ministry of Health
Grant Number: NW24-08-00157

  • 05/2024-12/2027

Brain organoids for target detection for precision treatment of schizophrenia

Principal Investigator: prof. MUDr. Tomáš Kašpárek, Ph.D.

CO-PI: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Ministry of Health
Grant Number: NW24-04-00158

  • 05/2024-12/2027

The function of FGFR2 cilia localization in glioblastoma pathogenesis

Principal Investigator: M.Sc. Michaela Bosáková, Ph.D.

CO-PI: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Ministry of Health
Grant Number: NW24-08-00364

  • 01/2024-12/2026

Prioritization of pathways linking aging and Alzheimer’s disease to cognitive decline and dementia

Partner: MSc. Dáša Bohačiaková, Ph.D.
Institutions: Amsterdam UMC / Aarhus University / Max-Planck Institute of Biophysics / The University of Bonn / University Hospital of Köln / University of Luxembourg / Masaryk University...

Funding agency:  Ministry of Education Youth and Sports, Czech Republic - Joint Programme
Grant Number: JPND2023-087

  • 01/2024-12/2026

Constructing the Developmental Atlas of Alzheimer’s Disease using Cerebral Organoids and Single-Cell Transcriptomics

Principal Investigator: MSc. Dáša Bohačiaková, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA24-12028S

  • 01/2024-12/2026

Development of brain organoid models to study the role of cellular senescence in the pathogenesis of glioblastoma

Principal Investigator: MUDr. Zdeněk Hodný, CSc.

CO-PI: MSc. Dáša Bohačiaková, Ph.D.
Institution: Czech Academy of Sciences/University hospital Hradec Králové/Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA24-11357S

  • 01/2024-12/2026

Humanized platform based on organoids for modeling mRNA-based therapeutic intervention in ischemic brain damage

Principal Investigator: Ing. Lukáš Valihrach, Ph.D.

CO-PI: M.Sc. Tereza Váňová, Ph.D., MSc. Dáša Bohačiaková, Ph.D.
Institution: Czech Academy of Sciences/Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA24-11364S

  • 01/2023–12/2026

ADDIT-CE: Alzheimer's Disease Diagnostics Innovation and Translation to Clinical Practice in Central Europe

Funding agency: European Union/Horizon Europe
Grant Number: 101087124

  • 07/2022-12/2025

National institute for Neurological Research

  • 05/2022-12/2025

Tracking SORLA function in patients with early onset Alzheimer’s disease

Principal Investigator: Jan Raška, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Ministry of Health, Czech Republic
Grant Number: NU22J-08-00075

  • 05/2021-12/2024

Pathogen-induced senescence as the initiation trigger for the onset of Alzheimer’s disease

Principal Investigator: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Ministry of Health, Czech Republic
Grant Number: NU21-08-00373

CLOSED

01/2022-12/2023

Title: Career Restart - Next generation sequencing in neural development and disease

Principal Investigator: Katerina Amruz Cerna, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of Masaryk University (GAMU)
Grant Number: MUNI/R/1321/2021

01/2021-12/2023

Title: Uncovering molecular mechanisms of Alzheimer’s disease initiation using brain organoids

Principal Investigator: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA21-21510S

07/2020-12/2023

Title: Identifying and treating SORL1-associated Alzheimer’s disease

Coordinator (Consortium): Henne Holstege
Partner: Dasa Bohaciakova, Ph.D.
Institutions: Amsterdam UMC, The Netherlands / Aarhus University, Denmark / Max-Planck Institute of Biophysics, Germany / Masaryk University, Brno, Czech Republic

Funding agency: The Netherlands Organization for Healthy, Research and Development / Innovation Fund Denmark / Ministry of Education Youth and Sports, Czech Republic / Federal Ministry of Education and Research, Germany
Grant Number: 8F20009

01/2021-12/2022

Title: Career Restart - Stem Cell-Based Models of Neurodegeneration

Principal Investigator: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of Masaryk University (GAMU)
Grant Number: MUNI/R/1697/2020

01/2020-12/2022

Title: New approaches to overcome therapeutic resistance of glioblastoma multiforme: Focus on cellular senescence and cerebral organoid model

Principal Investigator: Zdeněk Hodný, M.D., Ph.D.

CO-PI: Dasa Bohaciakova, Ph.D.

Institution: Institute of Molecular Genetics / University Hospital Hradec Kralove / Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of the Czech Republic (GACR)
Grant Number: GA20-15728S

05/2019 – 12/2022

Title: Clinically relevant biochemical, immunological and cellular biomarkers of Alzheimer's disease and aging

Principal Investigator: Pharm.Dr. Zdeněk Spáčil, Ph.D.

CO-PI: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Ministry of Health Research Programme 2015 - 2022
Grant Number: NV19-08-00472

10/2020-09/2021

Title: Neuronální excitabilita jako klíč k patofyziologii řady neuropsychiatrických onemocnění: snímání aktivity in vitro modelů lidské nervové tkáně technikou multielektrodových polí

Principal Investigator: doc. MUDr. Markéta Bébarová, Ph.D.

CO-PI: Dasa Bohaciakova, Ph.D.
Institution: Masaryk University, Brno, Czech Republic

Funding agency: Grant Agency of Masaryk University (GAMU)
Grant Number: MUNI/11/SUP/07/2020

03/2018 – 2020

Title: Transformative stem cell-based model of Alzheimer’s disease and advanced analytics to study the role of membrane lipids in the pathogenesis

Principal Investigator: Zdenek Spacil, PhD
Co-PI: Dasa Bohaciakova, PhD

Funding agency: Grant Agency of Masaryk University (GAMU)

2018 – 2020

Title: Functional studies of miRNAs and protein-coding genes involved in stem cell specification during neural development.

Principal Investigator: Dasa Bohaciakova, PhD

Funding agency: Grant Agency of the Czech Republic (GACR)

2018/01 – 2019/06

Title: Klinicky-využitelné neurální kmenové buňky a studium řízení jejich buněčného dělení.

Principal Investigator: Dasa Bohaciakova, PhD

Funding agency: Fond Neuron na podporu vedy - Neuron Impuls

2017

Title: In vitro modelování patologie Alzheimerovy choroby pomocí cerebrálních organoidů

Institutional support by Faculty of Medicne MU for junior researchers (2017, PI)

2015 – 2017

Title: The role of microRNA in cell cycle regulation and differentiation of human embryonic stem cell-derived neural stem cells.

Principal Investigator: Dasa Dolezalova, PhD

Funding agency: Grant Agency of the Czech Republic (GACR)

2016

Title: The role of microRNAs in the biology of human embryonic stem cells

Institutional support by Faculty of Medicine MU for junior researchers (2016, PI)

2009 - 2010

Title: The role of microRNAs and protein-coding genes in human embryonic stem cell response to DNA damage.

Principal Investigator: M.Sc. Dasa Dolezalova

Funding agency: Grant Agency of Masaryk University (GAMU)

2007 - 2009

Title: Analysis of Effects of Inhibition of Cyclin-Dependent Kinases on Differentiation of Human Embryonic Stem Cells.

Principal Investigator: Bc. Dasa Dolezalova

Funding agency: Grant Agency of Masaryk University (GAMU)

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