Barta Lab

14 Feb

Light-Responsive MicroRNAs in Human Retinal Tissue are Differentially Regulated by Distinct Wavelengths of Light

Did you know that humans possess #microRNAs that respond to #light regulation? And that these molecules exhibit a differential sensitivity to various wavelengths of light?

Link to study: https://www.biorxiv.org/content/10.1101/2023.02.10.528054v1

14 Sep 2022

We are hiring - PhD position

We are seeking a talented and motivated PhD student to join a research team headed by Dr. Tomas Barta at Masaryk University, Faculty of Medicine

27 Apr 2022

LuminoCell: Versatile and Affordable Platform for Real-Time Monitoring of Luciferase-Based Reporters

Our paper "LuminoCell: Versatile and Affordable Platform for Real-Time Monitoring of Luciferase-Based Reporters" has been published in Life Science Journal

Great collaboration between Bryja lab and Krejčí lab

7 Dec 2021

Lucie Pešková was awarded with the price "The award for excellent achievements from Vice-rector for research and doctoral studies"

Congratulations to Lucie Peskova my former PhD student, now at

@viennabiocenter

, for receiving The award for excellent achievements from Vice-rector for research and doctoral studies of

@muni_cz

Modelling Vision in a Dish

Research interests

Our research is primarily focused on human pluripotent stem cells. Pluripotent stem cells have the unique capability to differentiate into the three primary germ cell layers and therefore potentially to produce any cell or tissue of the body. Like all stem cells, pluripotent stem cells are able to self-renew, representing a theoretically unlimited source of cells. Our group uses induced pluripotent stem cells derived from skin fibroblasts cells. We use commercially available fibroblasts and reprogram them into pluripotent state.

What do we study:

Molecular mechanisms underlying cell fate switch during reprogramming with special focus on non-coding microRNA molecules.
Molecular mechanisms of differentiation of human pluripotent stem cells into retinal tissues.
How light irradiation regulates development of human retina
How light irradiation regulates circadian rhythms/molecular clock pathways

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