Laboratory of Stem Cell Biology and Vision Research

2021

• RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy

  RADASZKIEWICZ Tomasz Witold NOSKOVÁ Michaela GÖMÖRYOVÁ Kristína VONDÁLOVÁ BLANÁŘOVÁ Olga RADASZKIEWICZ Katarzyna Anna PÍCKOVÁ Markéta VÍCHOVÁ Ráchel GYBEĽ Tomáš KAISER Karol DEMKOVÁ Lucia KUČEROVÁ Lucia BÁRTA Tomáš POTĚŠIL David ZDRÁHAL Zbyněk SOUČEK Karel BRYJA Vítězslav

  Article in Periodical

  eLife, year: 2021, volume: 10, edition: October, DOI

2020

• miR-183/96/182 cluster is an important morphogenetic factor targetingPAX6expression in differentiating human retinal organoids

  PEŠKOVÁ Lucie JURČÍKOVÁ Denisa VÁŇOVÁ Tereza KŘIVÁNEK Jan CAPANDOVÁ Michaela ŠRÁMKOVÁ Zuzana ŠEBESTÍKOVÁ Jana KOLOUŠKOVÁ Magdaléna KOTASOVÁ Hana STREIT Libor BÁRTA Tomáš

  Article in Periodical

  Stem Cells, year: 2020, volume: 38, edition: 12, DOI

• Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

  BOSÁKOVÁ Michaela POOVAKULATHU ABRAHAM Sara NITĂ Alexandru HRUBA Eva BUCHTOVA Marcela TAYLOR S. Paige DURAN Ivan MARTIN Jorge SVOZILOVÁ Kateřina BÁRTA Tomáš VAŘECHA Miroslav BÁLEK Lukáš KOHOUTEK Jiri RADASZKIEWICZ Tomasz Witold PUSAPATI Ganesh V. BRYJA Vítězslav RUSH Eric T. THIFFAULT Isabelle NICKERSON Deborah A. BAMSHAD Michael J. ROHATGI Rajat COHN Daniel H. KRAKOW Deborah KREJČÍ Pavel

  Article in Periodical

  EMBO MOLECULAR MEDICINE, year: 2020, volume: 12, edition: 11, DOI

2019

• Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of secondary neurulation

  FEDOROVÁ Veronika VÁŇOVÁ Tereza ELREFAE Lina Mohamed Bahaael POSPÍŠIL Jakub PETRÁŠOVÁ Martina KOLAJOVÁ Veronika HUDACOVA Zuzana BANIARIOVÁ Jana BARÁK Martin PEŠKOVÁ Lucie BÁRTA Tomáš KAUCKÁ Markéta KILLINGER Michael VEČEŘA Josef BERNATÍK Ondřej ČAJÁNEK Lukáš HŘÍBKOVÁ Hana BOHAČIAKOVÁ Dáša

  Article in Periodical

  Stem Cell Research, year: 2019, volume: 40, edition: OCT 2019, DOI

• Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

  BOSÁKOVÁ Michaela NITĂ Alexandru GREGOR Tomáš VAŘECHA Miroslav GUDERNOVÁ Iva FAFÍLEK Bohumil BÁRTA Tomáš BASHEER Neha POOVAKULATHU ABRAHAM Sara BÁLEK Lukáš TOMANOVÁ Markéta FIALOVÁ KUČEROVÁ Jana BOSÁK Juraj POTĚŠIL David ZIEBA Jennifer SONG Jieun KONIK Peter PARK Sohyun DURAN Ivan ZDRÁHAL Zbyněk ŠMAJS David JANSEN Gert FU Zheng KO Hyuk Wan HAMPL Aleš TRANTÍREK Lukáš KRAKOW Deborah KREJČÍ Pavel

  Article in Periodical

  Proceedings of the National Academy of Sciences of the United States of America, year: 2019, volume: 116, edition: 10, DOI

• Human Embryonic Stem Cells Acquire Responsiveness to TRAIL upon Exposure to Cisplatin

  PEŠKOVÁ Lucie VINARSKÝ Vladimír BÁRTA Tomáš HAMPL Aleš

  Article in Periodical

  Stem Cells International, year: 2019, volume: 2019, edition: JAN 21 2019, DOI

• Ligase 3-mediated end-joining maintains genome stability of human embryonic stem cells

  KOHUTOVÁ Aneta RAŠKA Jan KRUTÁ Miriama ŠENEKLOVÁ Monika BÁRTA Tomáš FOJTÍK Petr JURÁKOVÁ Tereza WALTER Christi A. HAMPL Aleš DVOŘÁK Petr ROTREKL Vladimír

  Article in Periodical

  Faseb Journal, year: 2019, volume: 33, edition: 6, DOI

• Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts

  PEŠKOVÁ Lucie AMRUZ ČERNÁ Kateřina OPPELT Jan MRÁZ Marek BÁRTA Tomáš

  Article in Periodical

  Scientific reports, year: 2019, volume: 9, edition: OCT 31 2019, DOI

2018

• Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells

  RENZOVÁ Tereza BOHAČIAKOVÁ Dáša EŠNER Milan POSPÍŠILOVÁ Veronika BÁRTA Tomáš HAMPL Aleš ČAJÁNEK Lukáš

  Article in Periodical

  STEM CELL REPORTS, year: 2018, volume: 11, edition: 4, DOI

• Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs

  MEADER Ellie BÁRTA Tomáš MELGUIZO-SANCHIS Dario TILGNER Katarzyna MONTANER David EL-HAROUNI Ashraf A. ARMSTRONG Lyle LAKO Majlinda

  Article in Periodical

  Stem Cells, year: 2018, volume: 36, edition: 1, DOI